Intravenous dipyridamole (Persantine) increases coronary blood flow to the myocardium 2- come 3-fold. Viable myocardial cells take up thallium-201, a radionucleotide tracer, in proportion come blood flow. Hence, delay thallium redistribution complying with dipyridamole helps identify locations of ischemia (see image below). The test has actually a an adverse predictive worth (NPV) that 95-100% because that coronary artery disease in patients having actually vascular surgery; an unfavorable results have actually a likelihood ratio (LR) of 0.12, whereas confident results have actually an LR the 3.02.

You are watching: Radionuclide scan with thallium and dipyridamole


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Perioperative cardiac management. The sestamibi perfusion scan illustrates reversible ischemia in the anterior wall of the myocardium, compare rest and stress images.

Of note, be mindful when performing Persantine thallium scanning in patients with an underlying history of reactive airway disease, including asthma and also severe chronic obstructive pulmonary disease (COPD).


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Perioperative cardiac management. The transthoracic echocardiogram illustrates a parasternal lengthy axis watch of the left ventricle with kept cardiac function.
Perioperative cardiac management. The sestamibi perfusion scan illustrates reversible ischemia in the anterior wall surface of the myocardium, compare rest and stress images.
Perioperative cardiac management. Coronary angiogram revealing major left circumflex and also left anterior descending disease.


Davinder Jassal, MDAcademic Clinical Scientist, Cardiac scientific researches Division, St Boniface Hospital Research; Assistant Professor that Cardiology and also Radiology, Afffiliated Scientist of the academy of Biodiagnostics at the national Research the supervisory board of Canada; primary Investigator the the Cardiovascular Imaging Laboratory, institute of Cardiovascular sciences Davinder Jassal, MD is a member of the following medical societies: American college of Cardiology, American college of Physicians-American society of inner Medicine, American love Association, Canadian medical AssociationDisclosure: Nothing to disclose.


Sat Sharma, MD, FRCPCProfessor and also Head, division of Pulmonary Medicine, room of interior Medicine, college of Manitoba Faculty that Medicine; site Director, respiratory Medicine, St Boniface general Hospital, Canada satellite Sharma, MD, FRCPC is a member of the following medical societies: American Academy that Sleep Medicine, American university of Chest Physicians, American university of Physicians-American society of interior Medicine, American Thoracic Society, Canadian clinical Association, royal College of Physicians and also Surgeons the Canada, Royal society of Medicine, society of vital Care Medicine, world Medical AssociationDisclosure: Nothing come disclose.


Francisco Talavera, PharmD, PhDAdjunct Assistant Professor, university of Nebraska Medical facility College that Pharmacy; Editor-in-Chief, derekwadsworth.com medicine ReferenceDisclosure: received salary from derekwadsworth.com because that employment. For: derekwadsworth.com.

Donna Leco Mercado, MD, MD Donna Leco Mercado, MD, MD is a member that the complying with medical societies: Sigma Xi, The Scientific research study Honor SocietyDisclosure: Nothing to disclose.


William A Schwer, MDProfessor, room of household Medicine, Rush medical College; Chairman, department of household Medicine, Rush-Presbyterian-St Luke"s Medical facility William A Schwer, MD is a member that the complying with medical societies: American Academy of family members PhysiciansDisclosure: Nothing come disclose.

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George A Stouffer, III, MDErnest and Hazel Craige distinguished Professor of Medicine and also Cardiology, chef of Cardiology, college of north Carolina Medical center George A Stouffer, III, MD is a member of the following medical societies: Alpha Omega Alpha, American university of Cardiology, American college of Physicians, American love Association, Phi Beta Kappa, culture for Cardiovascular Angiography and InterventionsDisclosure: Nothing to disclose.


The authors and also editors the eMedicine gratefully recognize the contribute of ahead author, Tomas G Neilan, MD, come the breakthrough and writing of this article.