Reserpine, hydralazine, and also hydrochlorothiazide combine are used to law high blood push (hypertension).

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High blood press adds to the workload of the heart and arteries. If it proceeds for a lengthy time, the heart and also arteries may not function properly. This can damages the blood vessels of the brain, heart, and kidneys, resulting in a stroke, love failure, or kidney failure. High blood push may also increase the danger of heart attacks. These difficulties may be much less likely to happen if blood pressure is controlled.

Reserpine works by managing nerve impulses along particular nerve pathways. As a result, it acts on the heart and also blood vessels to lower blood pressure. Hydralazine functions by be safe blood vessels and increasing the it is provided of blood come the heart while reducing its work load. Hydrochlorothiazide is a thiazide diuretic (water pill) the helps to alleviate the amount of water in the human body by boosting the flow of urine. This likewise helps to reduced blood pressure.

This medicine is available only through your doctor"s prescription.

Before Using

In deciding to usage a medicine, the threats of taking the medication must be weighed versus the great it will certainly do. This is a decision you and also your physician will make. Because that this medicine, the complying with should be considered:


Tell your medical professional if friend have ever had any kind of unusual or allergy reaction come this medication or any other medicines. Also tell your health treatment professional if girlfriend have any other species of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, check out the label or package ingredient carefully.


Although there is no certain information comparing usage of this medicine in youngsters with use in other age groups, this medicine is not expected to reason different side effects or problems in kids than the does in adults.


Many medicines have not been studied specifically in enlarge people. Therefore, it may not be known whether they work exactly the same method they carry out in younger adults. Although over there is no specific information comparing use of reserpine, hydralazine, and also hydrochlorothiazide combination in the elderly through use in other period groups, this medicine is not intended to reason different side results or difficulties in older human being than the does in younger adults. However, drowsiness, dizziness, or faintness, or symptoms of too lot potassium loss may be much more likely to take place in the elderly, who room usually more sensitive to the impacts of this medicine. Also, this medicine might reduce tolerance to cold temperatures in elderly patients.



Studies in women indicate that this medication poses minimal danger to the infant as soon as used during breastfeeding.



There space no adequate research studies in women for determining child risk when using this medication throughout breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although specific medicines must not be offered together at all, in other cases two different medicines might be used together even if one interaction might occur. In these cases, her doctor may want to change the dose, or other precautions may be necessary. When you space taking this medicine, it is especially important the your healthcare skilled know if you room taking any type of of the medicines provided below. The adhering to interactions have actually been selected top top the communication of their potential significance and are not necessarily all-inclusive.

Using this medicine with any kind of of the complying with medicines is not recommended. Her doctor might decide no to law you with this medication or change some of the other medicines you take.


Using this medicine with any kind of of the complying with medicines is typically not recommended, yet may be required in some cases. If both medicines are prescribed together, your medical professional may adjust the sheep or how regularly you use one or both that the medicines.

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Using this medication with any type of of the complying with medicines may cause an enhanced risk of details side effects, but using both drugs may be the ideal treatment for you. If both drugs are prescribed together, your physician may readjust the sheep or how regularly you usage one or both of the medicines.

Aminolevulinic AcidBepridilCarbamazepineCholestyramineGinkgoGossypolLicoriceTopiramateYohimbine

Other interaction

Certain medicines should not be supplied at or approximately the time of eating food or eating certain varieties of food since interactions might occur. Making use of alcohol or tobacco with details medicines may additionally cause interaction to occur. The following interactions have been selected on the communication of your potential significance and are not necessarily all-inclusive.

Using this medicine with any of the adhering to may reason an enhanced risk of details side effects however may be inescapable in part cases. If used together, your medical professional may change the sheep or how often you usage this medicine, or offer you special instructions around the use of food, alcohol, or tobacco.

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Other Medical difficulties

The existence of other medical troubles may affect the usage of this medicine. Make sure you call your medical professional if you have any kind of other clinical problems, especially:

Allergies or various other breathing troubles such together asthma—Reserpine can reason breathing problemsType 2 diabetes mellitus—Hydrochlorothiazide may adjust the amount of diabetes medicine neededEpilepsyGallstones orStomach ulcer orUlcerative colitis—Reserpine increases activity of the stomach, which might make the problem worseGout (history of)—Hydrochlorothiazide may rise the lot of uric mountain in the blood, which can lead come goutHeart disease—Reserpine can reason heart rhythm troubles or sluggish heartbeat. Lowering blood pressure may worsen some conditionsKidney disease—Some patients may not carry out well when blood press is lower by this medicine. Impacts of hydralazine might be increased due to the fact that of slower removal native the body. If kidney an illness is severe, hydrochlorothiazide might not workLiver disease—If hydrochlorothiazide causes loss the too much water from the body, liver disease can end up being much worseLupus erythematosus (history of)—Hydrochlorothiazide may worsen the conditionMental depression (or background of)—Reserpine causes mental depression Pancreatitis (inflammation that pancreas)Parkinson"s disease—Reserpine can reason parkinsonism-like impacts PheochromocytomaStroke (recent)—Lowering blood pressure may make difficulties resulting indigenous this problem worse

Proper Use

In addition to the use of the medication your doctor has actually prescribed, treatment for her high blood pressure may encompass weight control and also care in the varieties of foods items you eat, specifically foods high in sodium. Your physician will tell girlfriend which that these room most vital for you. You should check with your doctor before changing your diet.