Medically the review by Alan Carter, Pharm.D. — created by Jill Seladi-Schulman, Ph.D. Top top December 19, 2018

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Acetaminophen (Tylenol) and ibuprofen (Advil) room both over-the-counter (OTC) medications that deserve to be provided to relieve pain.

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These drugs are two different species of ache relievers. Acetaminophen, sometimes provided as APAP, is its own type, when ibuprofen is a nonsteroidal anti-inflammatory medicine (NSAID).

Generally, it’s for sure to take it acetaminophen and also ibuprofen together, however you’ll desire to salary close fist to just how much you take of every medication.

The vital to safely acquisition acetaminophen and also ibuprofen is knowing how much you’re taking at a time and how often.

Acetaminophen dosage

The maximum safe dosage of acetaminophen for anyone end the age of 12 is 4,000 milligrams (mg) per day. However even this quantity can harm some people’s livers, for this reason aim for no an ext than 3,000 mg every day.

For children under the age of 12, it’s best to examine with their medical care provider to determine the safest sheep for their body weight.

Keep in mental that plenty of OTC medications contain acetaminophen in a range of doses, commonly 325 mg, 500 mg, or 650 mg.

Some instances of brand-name OTC medicines that might contain acetaminophen include:


Remember: when looking at labels, friend might also see acetaminophen noted as APAP.

Ibuprofen dosage

Avoid taking more that 1,200 mg of ibuprofen in a solitary day. OTC ibuprofen is often uncovered in 200 mg pills. This equates to 6 pills a day. Still, you should constantly verify exactly how much is in every pill.

Again, for children, it’s ideal to asking their healthcare provider around the safest dose for their weight.

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If you have prescription-strength ibuprofen, talk to her prescriber before mixing the with any type of other medications, including acetaminophen.


The recommended boundaries for adults and also children over 12 are:

3,000 mg every day the acetaminophen1,200 mg per day the ibuprofen

For children under the period of 12, contact their medical care provider or refer to the product brand for dosage guidelines.

You deserve to take ibuprofen and acetaminophen at the exact same time. Simply make sure to not take an ext than the encourage dose.

Some world experience part stomach or abdominal pain as soon as taking the two medicines together. In this case, it’s far better to alternate when you take each medication.

For example, you can take ib frames first, complied with by acetaminophen 4 hours later, and then repeat this process as needed.

You could additionally alternate days. For example, if you take it ibuprofen ~ above Monday, take acetaminophen on Tuesday and so on.